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This family consists of some not yet well characterized outer membrane proteins. The prototype of the family, yaiO of Escherichia coli, was initially predicted to be a transmembrane ß-barrel and later its localization to the outer membrane was proved by experimental methods. Its biological function remains unclear.
New Escherichia coli outer membrane proteins identified through prediction and experimental verification
Protein Sci. 2006 Apr;15(4):884-9. doi: 10.1110/ps.051889506. Epub 2006 Mar 7.