|Browse||Text search||Protein search||Domain search||Download||User manual||Related links||Citation & Contact|
This family consists of the major outer sneath proteins of Treponema lecithinolyticum and Treponema maltophilum. These proteins are localized in the outer membrane and form heat-modifiable, detergent and trypsin-stable complexes, suggesting a ß-barrel structure. However, they have not shown any channel activity and no sequence similarity to the MspA of Treponema denticola, therefore are chosen to comprise a different family.
Cloning and characterization of a gene (mspA) encoding the major sheath protein of Treponema maltophilum ATCC 51939(T)
J Bacteriol. 1999 Feb;181(3):1025-9. doi: 10.1128/JB.181.3.1025-1029.1999.
Cloning and characterization of a major surface protein (MspTL) of Treponema lecithinolyticum associated with rapidly progressive periodontitis
FEMS Microbiol Lett. 2002 Feb 5;207(2):185-92. doi: 10.1111/j.1574-6968.2002.tb11049.x.