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The Lipoprotein GNA1870 C-terminal Family [Function: Unknown] Seed alignment | Full alignment | Pfam page | ||||
GNA1870 is a surface exposed lipoprotein in Neisseria meningitidis that and is a potent antigen of Meningococcus. The structure of the C terminal domain consists of an anti-parallel ß barrel overlaid by a short alpha helical region. | ||||
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| Literature references | ||||
A meningococcal vaccine antigen engineered to increase thermal stability and stabilize protective epitopes Proc Natl Acad Sci U S A. 2015 Dec 1;112(48):14823-8. doi: 10.1073/pnas.1507829112. Epub 2015 Nov 16. PMID: 26627237 | ||||
Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules PLoS Pathog. 2012;8(10):e1002981. doi: 10.1371/journal.ppat.1002981. Epub 2012 Oct 25. PMID: 23133374 | ||||
Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates Nature. 2009 Apr 16;458(7240):890-3. doi: 10.1038/nature07769. Epub 2009 Feb 18. PMID: 19225461 | ||||
Solution structure of the immunodominant domain of protective antigen GNA1870 of Neisseria meningitidis J Biol Chem. 2006 Mar 17;281(11):7220-7. doi: 10.1074/jbc.M508595200. Epub 2005 Dec 31. PMID: 16407174 | ||||
[Pathological anatomy in The Netherlands showing new ways] Ned Tijdschr Geneeskd. 1991 Sep 28;135(39):1812-8. PMID: 1922546 | ||||
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