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The Lipoprotein GNA1870 Family [Function: Unknown] Seed alignment | Full alignment in OMPdb

GNA1870 is a surface exposed lipoprotein in Neisseria meningitidis that and is a potent antigen of Meningococcus. The structure of the C terminal domain consists of an anti-parallel beta barrel overlaid by a short alpha helical region.

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Literature references

Solution structure of the immunodominant domain of protective antigen GNA1870 of Neisseria meningitidis
J Biol Chem. 2006 Mar 17;281(11):7220-7. doi: 10.1074/jbc.M508595200. Epub 2005 Dec 31.
PMID: 16407174

Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules
PLoS Pathog. 2012;8(10):e1002981. doi: 10.1371/journal.ppat.1002981. Epub 2012 Oct 25.
PMID: 23133374

Pathological anatomy in The Netherlands showing new ways
Ned Tijdschr Geneeskd. 1991 Sep 28;135(39):1812-8.
PMID: 1922546

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