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The YbjH Family [Function: Non-specific channels] Seed alignment | Full alignment in OMPdb

YjbH is a family of Gram-negative ß-barrel outer-membrane lipoproteins that act as putative porins. YbjH is one of four gene-products expressed from an operon, yjbEFGH, which is regulated by the Rcs phosphorelay in a RcsA-dependent manner, similar to that of other exopolysaccharide biosynthetic pathways. It is highly possible that the yjbEFGH operon encodes a system involved in EPS secretion since none of the products is predicted to have enzymic activity, the products are all secreted and YbjH and F are predicted to be ß-barrel lipoproteins similar to porins. It may be that the operon products play some role in biofilm formation and/or matrix production


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Literature references

The yjbEFGH locus in Escherichia coli K-12 is an operon encoding proteins involved in exopolysaccharide production
Microbiology (Reading). 2007 Apr;153(Pt 4):1070-1080. doi: 10.1099/mic.0.2006/002907-0.
PMID: 17379715

The crystal structure of Escherichia coli group 4 capsule protein GfcC reveals a domain organization resembling that of Wza
Biochemistry. 2011 Jun 21;50(24):5465-76. doi: 10.1021/bi101869h. Epub 2011 May 27.
PMID: 21449614


Elixir UTH dib compgen