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The DUF2860 (Cj0561c) Family [Function: Adhesion] Seed alignment | Full alignment | Pfam page | TC-DB page

Cj0561c is a probable membrane fusion protein and contributes to intestinal colonization. Cj0561c is the only characterized member of DUF2860. Cj0561c is encoded as a membrane transporter gene whose transcription is inhibited by CmeR in Campylobacter jejuni.

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Literature references

CmeR-dependent gene Cj0561c is induced more effectively by bile salts than the CmeABC efflux pump in both human and poultry Campylobacter jejuni strains
Res Microbiol. 2011 Dec;162(10):991-8. doi: 10.1016/j.resmic.2011.08.001. Epub 2011 Aug 31.
PMID: 21920435

CmeR functions as a pleiotropic regulator and is required for optimal colonization of Campylobacter jejuni in vivo
J Bacteriol. 2008 Mar;190(6):1879-90. doi: 10.1128/JB.01796-07. Epub 2008 Jan 4.
PMID: 18178742

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