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The PorP_SprF Family [Function: Unknown] Seed alignment | Full alignment in OMPdb

SprP is associated with the outer membrane of Cytophaga hutchinsonii. It is suggested that SprP is involved in protein secretion, a hypothesis made due to its sequence similarity with PorP that is responsible for the secretion of gingipain protease virulence factors in Porphyromonas gingivalis type IX secretion system (T9SS) and SprF that is crucial for the delivery of the gliding motility machinery components to the cell surface.


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Literature references

Deletion of the Cytophaga hutchinsonii type IX secretion system gene sprP results in defects in gliding motility and cellulose utilization
Appl Microbiol Biotechnol. 2014 Jan;98(2):763-75. doi: 10.1007/s00253-013-5355-2. Epub 2013 Nov 21.
PMID: 24257839


Elixir UTH dib compgen