Browse Text search Protein search Domain search Download User manual Related links Citation & Contact

The Alginate Export Porin (algE) Family [Function: Biogenesis/Secretion] Seed alignment | Full alignment in OMPdb

Proteins of the AEP family are believed to export alginate (an acidic polysaccharide), across the outer membrane of Gram-negative bacteria. These proteins span the outer membrane forming a large ß-barrel comprised of 18 beta sheets, as the 3D structure of one of the family's members suggests.

Specify pHMMs' % coverageUnspecified More than   
Representative image:  fam_img

Literature references

The Azotobacter vinelandii gene algJ encodes an outer-membrane protein presumably involved in export of alginate
Microbiology (Reading). 1996 Apr;142 ( Pt 4):873-80. doi: 10.1099/00221287-142-4-873.
PMID: 8936313

Overexpression of algE in Escherichia coli: subcellular localization, purification, and ion channel properties
J Bacteriol. 1994 Sep;176(18):5639-47. doi: 10.1128/jb.176.18.5639-5647.1994.
PMID: 7521870

Structural basis for alginate secretion across the bacterial outer membrane
Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13083-8. doi: 10.1073/pnas.1104984108. Epub 2011 Jul 21.
PMID: 21778407

Dual roles of Pseudomonas aeruginosa AlgE in secretion of the virulence factor alginate and formation of the secretion complex
Appl Environ Microbiol. 2013 Mar;79(6):2002-11. doi: 10.1128/AEM.03960-12. Epub 2013 Jan 18.
PMID: 23335756

Proteins in this family with 3D-structure


Elixir UTH dib compgen