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The Alginate Export Porin (algE) Family [Function: Biogenesis/Secretion] Seed alignment | Full alignment in OMPdb | |
Proteins of the AEP family are believed to export alginate (an acidic polysaccharide), across the outer membrane of Gram-negative bacteria. These proteins span the outer membrane forming a large ß-barrel comprised of 18 beta sheets, as the 3D structure of one of the family's members suggests. | |
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| Literature references | |
The Azotobacter vinelandii gene algJ encodes an outer-membrane protein presumably involved in export of alginate Microbiology (Reading). 1996 Apr;142 ( Pt 4):873-80. doi: 10.1099/00221287-142-4-873. PMID: 8936313 | |
Overexpression of algE in Escherichia coli: subcellular localization, purification, and ion channel properties J Bacteriol. 1994 Sep;176(18):5639-47. doi: 10.1128/jb.176.18.5639-5647.1994. PMID: 7521870 | |
Structural basis for alginate secretion across the bacterial outer membrane Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13083-8. doi: 10.1073/pnas.1104984108. Epub 2011 Jul 21. PMID: 21778407 | |
Dual roles of Pseudomonas aeruginosa AlgE in secretion of the virulence factor alginate and formation of the secretion complex Appl Environ Microbiol. 2013 Mar;79(6):2002-11. doi: 10.1128/AEM.03960-12. Epub 2013 Jan 18. PMID: 23335756 | |
| Proteins in this family with 3D-structure | |
P18895 | |
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