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The capsule assembly protein Wzi Family [Function: Biogenesis/Secretion] Seed alignment | Full alignment | Pfam page | TC-DB page | ||||
This family consists of homologs to the wzi protein of E.coli. Wzi was found to be involved in the surface assembly of the Escherichia coli K30 group 1 capsule, participating in the translocation of group 1 capsular polysaccharide in co-operation with the wza complex. Wzi is an outer membrane monomeric 18-stranded ß-barrel protein. Homologs are also found in genera Klebsiella pneumoniae, Acinetobacter, Psychrobacter, Shewanella oneidensis, Rhodobacter sphaeroides, Idiomarina loihiensis and Microbulbifer degradans. | ||||
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| Literature references | ||||
EasyPrimer: user-friendly tool for pan-PCR/HRM primers design. Development of an HRM protocol on wzi gene for fast Klebsiella pneumoniae typing Sci Rep. 2020 Jan 28;10(1):1307. doi: 10.1038/s41598-020-57742-z. PMID: 31992749 | ||||
Molecular Characterization of Carbapenem Resistant Klebsiella pneumoniae and Klebsiella quasipneumoniae Isolated from Lebanon Sci Rep. 2019 Jan 24;9(1):531. doi: 10.1038/s41598-018-36554-2. PMID: 30679463 | ||||
Key diffusion mechanisms involved in regulating bidirectional water permeation across E. coli outer membrane lectin Sci Rep. 2016 Jun 20;6:28157. doi: 10.1038/srep28157. PMID: 27320406 | ||||
Genotypes of Ciprofloxacin-Resistant Klebsiella pneumoniae in Korea and Their Characteristics According to the Genetic Lineages Microb Drug Resist. 2015 Dec;21(6):622-30. doi: 10.1089/mdr.2015.0001. Epub 2015 Jul 24. PMID: 26207318 | ||||
wzi Gene sequencing, a rapid method for determination of capsular type for Klebsiella strains J Clin Microbiol. 2013 Dec;51(12):4073-8. doi: 10.1128/JCM.01924-13. Epub 2013 Oct 2. PMID: 24088853 | ||||
Encapsulating bacteria Structure. 2013 May 7;21(5):692-3. doi: 10.1016/j.str.2013.04.011. PMID: 23664360 | ||||
Wzi is an outer membrane lectin that underpins group 1 capsule assembly in Escherichia coli Structure. 2013 May 7;21(5):844-53. doi: 10.1016/j.str.2013.03.010. Epub 2013 Apr 25. PMID: 23623732 | ||||
Three-dimensional structure of Wza, the protein required for translocation of group 1 capsular polysaccharide across the outer membrane of Escherichia coli J Biol Chem. 2004 Jul 2;279(27):28227-32. doi: 10.1074/jbc.M402913200. Epub 2004 Apr 16. PMID: 15090537 | ||||
A novel outer membrane protein, Wzi, is involved in surface assembly of the Escherichia coli K30 group 1 capsule J Bacteriol. 2003 Oct;185(19):5882-90. doi: 10.1128/jb.185.19.5882-5890.2003. PMID: 13129961 | ||||
Translocation of group 1 capsular polysaccharide in Escherichia coli serotype K30. Structural and functional analysis of the outer membrane lipoprotein Wza J Biol Chem. 2003 Dec 12;278(50):49763-72. doi: 10.1074/jbc.M308775200. Epub 2003 Sep 30. PMID: 14522970 | ||||
| Proteins in this family with 3D-structure | ||||
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