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The Glucose-selective OprB Porin (OprB) Family [Function: Specific channels] Seed alignment | Full alignment in OMPdb | |
The OprB family includes the Pseudomonas aeruginosa porin B (OprB), a substrate-selective channel for a variety of different sugars, which is probably restricted to carbohydrates and facilitates glucose fusion across the outer membrane. Homologs are also found in Pseudomonas chlororaphis, Burkholderia cepacia, Pseudomonas fluorescens, Acinetobacter calcoaceticus and Xanthomonas campestris. The high-affinity glucose transport system is primarily specific for glucose and well conserved, although the outer membrane components may differ in channel architecture and specificity for other carbohydrates. Similar to other porins, these proteins form 16-stranded beta barrels. | |
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Literature references | |
Multiple environmental factors regulate the expression of the carbohydrate-selective OprB porin of Pseudomonas aeruginosa Can J Microbiol. 1999 Dec;45(12):1033-42. PMID: 10696483 | |
Channel specificity and secondary structure of the glucose-inducible porins of Pseudomonas spp J Bioenerg Biomembr. 1998 Jun;30(3):257-67. doi: 10.1023/a:1020596820314. PMID: 9733092 | |
The OprB porin plays a central role in carbohydrate uptake in Pseudomonas aeruginosa J Bacteriol. 1995 Jun;177(11):3021-6. doi: 10.1128/jb.177.11.3021-3026.1995. PMID: 7768797 | |
Cloning and nucleotide sequence of the Pseudomonas aeruginosa glucose-selective OprB porin gene and distribution of OprB within the family Pseudomonadaceae Eur J Biochem. 1994 Mar 1;220(2):505-12. doi: 10.1111/j.1432-1033.1994.tb18649.x. PMID: 8125108 | |
Proteins in this family with 3D-structure | |
A5VZA8 |
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