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The Type Specific Antigen (TSA) Family [Function: Unknown] Seed alignment | Full alignment in OMPdb

This family consists of several antigenic variants in Rickettsia tsutsugamushi, and a type-specific antigen (TSA) of 56-kilodaltons located on the rickettsial surface is responsible for the variation. TSA proteins are probably integral membrane proteins (description adapted from Pfam database).


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Literature references

Purification and partial characterization of a type-specific antigen of Rickettsia tsutsugamushi
Infect Immun. 1989 May;57(5):1427-31. doi: 10.1128/IAI.57.5.1427-1431.1989.
PMID: 2496028

Diversity of immunodominant 56-kDa type-specific antigen (TSA) of Rickettsia tsutsugamushi. Sequence and comparative analyses of the genes encoding TSA homologues from four antigenic variants
J Biol Chem. 1992 Jun 25;267(18):12728-35.
PMID: 1618776


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