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The Putative outer membrane protein (HP_OMP_2) Family [Function: Adhesion] Seed alignment | Full alignment | Pfam page
This family consists of several outer membrane proteins found only in Helicobacter pylori, which is the causative agent of gastritis and peptic ulceration in humans. The outer membrane proteome profile of Helicobacter pylori differs from that of other Gram-negative bacteria. Outer membrane proteins of Helicobacter pylori are characterized mainly as adhesins and porins, while extensive C-terminal sequence similarity between these proteins has been used to define this large paralogous family. Hof (H. pylori outer membrane protein family) is another Omps subfamily composed of 8 members, two of which (HofC/Hp0486 and HofD/Hp0487) are exported via an N-terminal signal peptide.
Identification of new protein coding sequences and signal peptidase cleavage sites of Helicobacter pylori strain 26695 by proteogenomics
J Proteomics. 2013 Jun 28;86:27-42. doi: 10.1016/j.jprot.2013.04.036. Epub 2013 May 9.
The complete genome sequence of the gastric pathogen Helicobacter pylori
Nature. 1997 Aug 7;388(6642):539-47. doi: 10.1038/41483.