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Lysenin is a PFT of Eisena fetida and a member of the aerolysin family. It is a nonamer and forms an 18-strand smooth-walled tubular beta barrel attached to the outside by the C-terminal domains. It is a mushroom-like structure which has a transmembrane pore with a central stem built of a long beta barrel. Having a uniform and stable beta barrel through the entire length of protein makes lysenin an exception among PFTs.
Crystal structure of an invertebrate cytolysin pore reveals unique properties and mechanism of assembly
Nat Commun. 2016 May 12;7:11598. doi: 10.1038/ncomms11598.